Skeletal muscle responds to passive overstretch through read more sarcomerogenesis, the creation and serial deposition of new sarcomere units.Sarcomerogenesis is critical to muscle function: It gradually re-positions the muscle back into its optimal operating regime.Animal models of immobilization, limb lengthening, and tendon transfer have provide
Background.The relevance of the article is connected with the necessity to reflect on the content of the main scientific and organizational stages in the evolution of the research activity of the Psychological Institute on the eve of its 110th anniversary.Objective.On the basis of documentary sources to carry out a historical and psychological reco
Here we have shown for the first time altered expression of the vascular smooth muscle (VSM) KATP channel subunits in segments of the human internal mammary artery (HIMA) in patients with type-2 diabetes mellitus (T2DM).Functional properties of vascular KATP channels in the presence of T2DM, and the interaction between pet calming peanut butter its
Abstract Designing molecules with desirable properties is a critical endeavor in drug discovery.Because of recent advances in deep learning, molecular generative models have been developed.However, the existing compound exploration models often disregard the important issue of ensuring the feasibility of organic synthesis.To address this issue, we
F-spondin, an extracellular matrix protein, is an important player in embryonic morphogenesis and CNS development, but its presence read more and role later in life remains largely unknown.We generated a transgenic zebrafish in which GFP is expressed under the control of the F-spondin (spon1b) promoter, and used it in combination with complementary